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The recommended dosage and dosing schedule for Niranib 100mg (Niraparib) depend on several factors, including the patient's body weight, renal function, and any potential dose modifications due to side effects or tolerability issues. Generally, the standard starting dose of Niraparib for maintenance treatment of ovarian cancer is 300 mg once daily, taken orally, with or without food.
However, dose adjustments may be necessary based on individual patient characteristics. For patients who weigh less than 77 kg (170 lbs) or who have baseline Niranib 100mg (Niraparib) moderate renal impairment (creatinine clearance 30-59 mL/min), the recommended starting dose is 200 mg once daily. Patients should be monitored closely for any signs of toxicity or adverse reactions.
The dosing schedule for Niraparib involves continuous daily administration, with treatment typically initiated within 8 weeks of completing platinum-based chemotherapy. The duration of treatment may vary depending on the individual patient's response and tolerability, as well as the treating physician's assessment.
During treatment with Niraparib, patients are regularly monitored by healthcare providers to assess treatment response and manage any potential side effects. Blood counts, including complete blood counts with differential, should be monitored periodically to assess for hematologic toxicity, such as thrombocytopenia, neutropenia, or anemia.
In cases of hematologic toxicity or other adverse reactions, dose modifications or interruptions may be necessary to manage side effects while maintaining the therapeutic benefit of Niraparib. Healthcare providers may temporarily hold treatment, reduce the dose, or discontinue therapy altogether based on the severity of adverse events and the patient's overall clinical status.
Patients should adhere to the prescribed dosage and dosing schedule for Niraparib as directed by their healthcare provider and should not adjust their dose without consulting a healthcare professional. It's essential to communicate any concerns or side effects experienced during treatment with Niraparib to the healthcare team promptly.
Overall, the recommended dosage and dosing schedule for Niranib 100mg (Niraparib) are tailored to each individual patient's needs and treatment response, with close monitoring and potential dose adjustments to optimize therapeutic outcomes and minimize adverse effects.
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