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It seems there might be a slight confusion in your query. Panovir is not the same as Sofosbuvir-Velpatasvir. Panovir is a brand name for an antiviral medication called Foscarnet, used primarily in the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. On the other hand, Sofosbuvir-Velpatasvir is a combination medication used to treat chronic hepatitis C virus (HCV) infection.

However, I can provide information on Panovir (Sofosbuvir-Velpatasvir) as it's a significant advancement in the treatment of hepatitis C.

Sofosbuvir-Velpatasvir is a combination medication that has revolutionized the treatment of chronic hepatitis C virus (HCV) infection. It combines two direct-acting antiviral agents, Sofosbuvir and Velpatasvir, in a single pill, offering a highly effective and convenient treatment option for patients with HCV.

Sofosbuvir is a nucleotide analog NS5B polymerase inhibitor, while Velpatasvir is an NS5A inhibitor. Together, they target different steps of the HCV replication cycle, effectively suppressing viral replication and preventing the virus from multiplying within the body.

One of the most significant advantages of Sofosbuvir-Velpatasvir is its high cure rates across all genotypes of HCV infection. Clinical trials have demonstrated cure rates exceeding 95% in both treatment-naive and treatment-experienced patients, including those with compensated cirrhosis.

Another benefit of Sofosbuvir-Velpatasvir is its tolerability and convenience. The once-daily, single-tablet regimen is well-tolerated by most patients and offers a simplified treatment approach compared to older interferon-based regimens, which were associated with significant side effects.

Additionally, Sofosbuvir-Velpatasvir has a shorter treatment duration compared to some previous regimens, typically ranging from 8 to 12 weeks depending on factors such as HCV genotype and the presence of cirrhosis. This shorter duration not only improves patient adherence but also reduces the overall cost and burden of treatment.

In conclusion, Sofosbuvir-Velpatasvir represents a significant advancement in the field of hepatitis C treatment. Its high efficacy, tolerability, and convenience have made it a preferred choice for clinicians and patients alike, offering hope for the eradication of HCV infection on a global scale. However, as with any medication, it's essential to consult with a healthcare professional to determine the most appropriate treatment regimen based on individual patient factors and medical history.

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